Midland picked up its first run of the evening on an RBI-single in the bottom of the first, giving the Lady Mustangs a 1-0 lead.
Bethany Pate hit safely for the Lady Hounds in the top of the second, but her base hit came with two outs and a strikeout ended the frame for Salem.
Then in the bottom of the third, Midland crossed the plate three more times.
Farrah Turner started things off with a hit for the Lady Mustangs and she then came home on a triple off the bat of Nikki Emerson for Midland's first tally of the inning.
One hitter later, Raigan Skidmore plated Emerson with an RBI-single and Midland wrapped up the scoring in the stanza with a sacrifice fly. The Lady Mustangs were poised for more runs in the third, but a nifty double-play from the Lady Greyhounds ended the inning with Midland on top 4-0.
Laci Long led off the top of the fourth with a screaming triple that glanced off the right fielder's glove, but Salem was unable to bring Long home from third.
In the visitor's half of the fifth, the Lady Hounds had another shot at scoring, but also came up short.
Shelby York walked and Pate reached on an error with two outs in the frame, but they were left stranded at second and third after a strikeout ended the inning.
Salem did push a run across the plate in the top of the sixth.
Long jump-started the offense with her second hit of the game and later stole second. She moved to third as Terra Kinder reached first on a fielding error.
Next up, Ashley Brooks hit into a fielder's choice at first and Long was tagged out trying to come home on the play for the second out of the inning.
But Allison Loomis came through with a bloop hit to short left that scored Kinder.
But that was as close as Salem could get and Midland won the distinct tournament title with the 4-1 victory.
Brooks worked all seven innings in the circle for the Lady Hounds, giving up eight hits while fanning five and hitting one batter.
The Lady Greyhounds bounced back by pushing past the Riverside Lady Rebels 6-2 in the opening round of the 2A North Regional Tournament April 25 in Melbourne.
The victory gives Salem a spot in the 2A State Tournament.